HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-3'-chloroacetophenone → 3-Amino-5-chloro-2-(3-chlorobenzoyl)-1-(ethoxycarbonyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-3'-chloroacetophenone | HCID 38738 | — |
| Reactant | Ethyl 4-chloro-2-cyanophenylcarbamate | HCID 21779762 | — |
| Product | 3-Amino-5-chloro-2-(3-chlorobenzoyl)-1-(ethoxycarbonyl)indole | HCID 18367741 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 2 of Example 1 from 5-chloro-2-[(ethoxycarbonyl)amino]benzonitrile (K. O. Geolotte et al, J. Heterocyclic Chem., 1990, 27, 1549) and 2-bromo-3′-chloroacetophenone (M. Kihara et al., Tetrahedron, 1992, 48, 67-78).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06277878B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-bc3aed57918240059754744646cf72ff |
| Source note | uspto-grants-2001_08 |