HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 5-Chloro-1h-indole-2-carboxylic acid [(methoxy-methyl-carbamoyl)-methyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | N-[(5-chloro-1H-indol-2-yl)carbonyl]glycine | HCID 11436686 | — |
| Reactant | Methoxymethanamine hydrochloride | HCID 21959107 | — |
| Product | 5-Chloro-1h-indole-2-carboxylic acid [(methoxy-methyl-carbamoyl)-methyl]-amide | HCID 53861527 | — |
Reaction Steps
Methoxymethylamine hydrochloride (1.0 mmol) and [(5-chloro-1H-indole-2-carbonyl)-amino]-acetic acid (1.0 mmol) were coupled according to Procedure A. The resulting solid was suspended in ether, filtered and dried: Yield 158 mg, 53%; PBMS 296/298 (MH+, 100%);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06277877B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-7bf8fa9d80634bd19d45a6096bd50611 |
| Source note | uspto-grants-2001_08 |