5,7-dichloro-1H-indole-2-carboxylic Acid → HCID 21710747, compound

HRID 651172Notes

Reaction equation

HRID 651172 reaction equation
[Cl:1][C:2]1[C:3]([N+:16]([O-:18])=[O:17])=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11]([O:13]CC)=[O:12])=[CH:5]2.ClC1C=C2C(=C(Cl)C=1)NC(C(O)=O)=C2>>[N+:16]([C:3]1[C:2]([Cl:1])=[CH:10][CH:9]=[C:8]2[C:4]=1[CH:5]=[C:6]([C:11]([OH:13])=[O:12])[NH:7]2)([O-:18])=[O:17]

Participants

3

Reactant 2

HCID 49832385,7-dichloro-1H-indole-2-carboxylic AcidHCID 21710828HCID 21710828, compound

Product 1

HCID 21710747HCID 21710747, compound

Procedure

The title compound was prepared by hydrolysis of ethyl 5-chloro4-nitro-1H-indole-2-carboxylate as described for the preparation of 5,7-dichloro-1H-indole-2-carboxylic acid.

Sources & evidence

ORD record
ord-b8e4f742412145cfa473194e2db941bf
Source dataset
uspto-grants-2001_08
Patent number
US06277877B1

Reaction notes

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