5-Chloro-1H-indole-2-carboxylic acid → HCID 53991627, compound

HRID 651176Notes

Reaction equation

HRID 651176 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11]([OH:13])=O)=[CH:5]2.[NH2:14][CH:15]([CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([C:30]#[N:31])[CH:25]=1)[C:16]([N:18]1[CH2:22][CH2:21][S:20][CH2:19]1)=[O:17]>>[C:30]([C:26]1[CH:25]=[C:24]([CH2:23][CH:15]([NH:14][C:11]([C:6]2[NH:7][C:8]3[C:4]([CH:5]=2)=[CH:3][C:2]([Cl:1])=[CH:10][CH:9]=3)=[O:13])[C:16]([N:18]2[CH2:22][CH2:21][S:20][CH2:19]2)=[O:17])[CH:29]=[CH:28][CH:27]=1)#[N:31]

Participants

3

Reactant 2

HCID 826935-Chloro-1H-indole-2-carboxylic acidHCID 21710809HCID 21710809, compound

Product 1

HCID 53991627HCID 53991627, compound

Procedure

From 5-chloro-1H-indole-2-carboxylic acid and (±)-2-amino-3-(3cyano-phenyl)-1-thiazolidin-3-yl-propan-1-one.

Sources & evidence

ORD record
ord-16759d5027ce4d09932d7cccb282c1b0
Source dataset
uspto-grants-2001_08
Patent number
US06277877B1

Reaction notes

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