HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- → HCID 69688105, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| Reactant | Isoindoline | HCID 422478 | — |
| Product | HCID 69688105 | HCID 69688105 | — |
Reaction Steps
N-t-Boc-L-phenylalanine (1 mmol) and isoindoline (J. Org. Chem. 1988, 53, p5382, 70-80% purity, 1 mmol) were coupled according to Procedure A and the product purified by chromatography on silica gel eluted with 20% and 50% ethyl acetate-hexanes giving an amber oil (88 mg, 23%): TSPMS 367 (MH+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06277877B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-e47e87ae3f9646aabd9d759ccfbf0641 |
| Source note | uspto-grants-2001_08 |