HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 651247Generated: October 30, 2026
2-Chloroacrylonitrile → HCID 21711804, compound
https://huagongshe.com/reaction/651247
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Chloroacrylonitrile | HCID 70198 | — |
| Reactant | 3-Azido-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one | HCID 10932520 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 21711804 | HCID 21711804 | — |
Reaction Steps
A mixture of 3-azido-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine (1.01 g) and 2-chloroacrylonitrile (0.95 g) in water (5 ml) is stirred at about 80° C. for 18 hours. Excess 2-chloroacrylonitrile is distilled off in vacuo, and the precipitated product is filtered off, washed with water and dried (yield 1.1 g; 87% of theory), m.p. 214-216° C. (recrystallization from ethyl acetate/toluene).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06277999B1 |
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| Source dataset | uspto-grants-2001_08 |
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| ORD ID | ord-d510fa2bebd14e89b7752766e94a7a14 |
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| Source note | uspto-grants-2001_08 |
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