HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl chloroformate → 4-methoxy-2-oxo-2,3-dihydrobenzimidazole-1-carboxylic Acid Phenyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | 4-methoxy-1H-benzo[d]imidazol-2(3H)-one | HCID 12926628 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 4-methoxy-2-oxo-2,3-dihydrobenzimidazole-1-carboxylic Acid Phenyl Ester | HCID 70126672 | — |
Reaction Steps
To a solution of 4-methoxy-2-oxo-2,3-dihydrobenzimidazole (24 g; 0.146 mol) in pyridine (200 ml), phenylchloroformate (18.4 ml; 0.146 mol) was added dropwise. The reaction mixture was refluxed for 14 hours then was poured into ice-water. The precipitated solid was collected and dried to give the title compound. 30 g; m.p. 204-205° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06281218B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-f2ca2589acc941b49c79a3176a633e7e |
| Source note | uspto-grants-2001_08 |