Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Diphenyl[2-(trifluoromethyl)phenyl]phosphane | HCID 303893 | — |
| Catalyst | Palladium Chloride | HCID 24290 | — |
| Product | Methyl isobutyrate | HCID 11039 | — |
| Product | Methyl butyrate | HCID 12180 | — |
Reaction Steps
The autoclave was charged with 0.3 gms of palladium chloride, 5 gms o-trifluoromethylphenyldiphenylphosphine, 10 mls of methanol and 50 ml of p-dioxane. After flushing with nitrogen, the autoclave was pressurized with carbon monoxide to 800 psig and heated to 120 degrees C. with stirring. 10 gms of liquid propylene was added and the reaction continued at 120° C. and 100 psig for 3 hours. The autoclave was then cooled and the reaction fluid analyzed by gas chromatography. A methyl isobutyrate:methyl n-butyrate ratio of 7.1:1 was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04612390 |
|---|
| Source dataset | uspto-grants-1986_09 |
|---|
| ORD ID | ord-e5490df9d8cf467daca53ea437840a1c |
|---|
| Source note | uspto-grants-1986_09 |
|---|
