HuagongsheHuagongshe Chemistry Print Report · For research reference only
Mandelic Acid → Sotalol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Mandelic Acid | HCID 1292 | — |
| Reactant | Dexsotalol Hydrochloride | HCID 165245 | — |
| Product | Sotalol | HCID 5253 | — |
Reaction Steps
In addition, using chemical method as described by Le Garrec (1987), enriched d-sotalol hydrochloride and l-sotalol hydrochloride were prepared using mandelic acid and subjected to conversion to the base form, chiral separation and reconversion to hydrochloride salt was carried out. The details of these procedures are given below:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06281246B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-b1da450602074d29b7a1aa7f0ca08711 |
| Source note | uspto-grants-2001_08 |