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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 651496Generated: October 25, 2026

Potassium Carbonate → Sotalol

https://huagongshe.com/reaction/651496

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantSotalol HydrochlorideHCID 66245—
SolventWaterHCID 962—
ProductSotalolHCID 5253—

Reaction Steps

In 2 lit. round bottom flask, in 450 ml of water, (±) sotalol hydrochloride (200 g) was added under stirring at room temperature. Under stirring, a solution of 500 g of potassium carbonate in 300 ml of water was added. The stirring was continued for 48 hours. Solid material was separated to give 107 g of (±) sotalol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06281246B1
Source datasetuspto-grants-2001_08
ORD IDord-83949e398a5643a2bda1cdc453c2439c
Source noteuspto-grants-2001_08