Potassium ethanethioate → HCID 86585314, compound

HRID 651501Notes

Reaction equation

I[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([C@H:13]2[CH2:30][C@@:28]3([CH3:29])[C@@H:24]([CH2:25][CH2:26][C@@H:27]3[OH:31])[C@H:23]3[C@H:14]2[C:15]2[CH:16]=[CH:17][C:18]([OH:32])=[CH:19][C:20]=2[CH2:21][CH2:22]3)=[CH:9][CH:8]=1.[C:33]([O-])(=[S:35])[CH3:34].[K+]>>[C:33]([CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([C@H:13]2[CH2:30][C@@:28]3([CH3:29])[C@@H:24]([CH2:25][CH2:26][C@@H:27]3[OH:31])[C@H:23]3[C@H:14]2[C:15]2[CH:16]=[CH:17][C:18]([OH:32])=[CH:19][C:20]=2[CH2:21][CH2:22]3)=[CH:9][CH:8]=1)(=[S:35])[CH3:34]

Participants

Reactant 2

HCID 23670855Potassium ethanethioate

HCID 70019444HCID 70019444, compound

Product 1

HCID 86585314HCID 86585314, compoundYield 82.2%

Procedure

The operation is carried out as in Stage E of Example 8 starting with 1.18 g of the product obtained in Stage D and 460 mg of potassium thioacetate. 850 mg of expected product is obtained. M.p. # 90° C.

Sources & evidence

ORD record: ord-514b49d5b1954a9cbfd73f2cc677d67b
Source dataset: uspto-grants-2001_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06281204B1

Reaction notes

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