Methanol → HCID 21138126, compound

Participants

Reaction Steps

3.39 g of the product obtained in Example 61 in 16.6 cm3 of pyridine, 3.14 cm3 of acetic anhydride and 154 mg of dimethylaminopyridine are agitated for 45 minutes at ambient temperature. 5.4 cm3 of methanol is added, followed by agitation for 10 minutes, evaporating the solvents, the residue is taken up in ethyl acetate, followed by washing with an aqueous solution of M hydrochloric acid, then with sodium chloride, drying and evaporating the solvent. After chromatographing the residue on silica (eluant: ethyl acetate-cyclohexane 5-5 then 3-7), 3.25 g of expected product is obtained.

Provenance & Evidence