HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-methoxynaphthalene-2-sulfonyl Chloride → HCID 53883616, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-methoxynaphthalene-2-sulfonyl Chloride | HCID 10515266 | — |
| Reactant | 6-Chlorobenzo[b]thiophene-2-sulfonyl chloride | HCID 15158641 | — |
| Reactant | HCID 20680740 | HCID 20680740 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 53883616 | HCID 53883616 | — |
Reaction Steps
The title compound is prepared in CH2Cl2 instead of CH3CN from 7-(3-(S)-amino-2-oxopyrrolidin-1-ylmethyl)-2-chloro-quinoline hydrochloride as described in EXAMPLE 1, Part K using 6-chloro-benzo[b]thiophene-2-sulfonyl chloride as prepared in EXAMPLE 9, Parts A, B and C in place of 7-methoxynaphthalene-2-sulfonyl chloride. The crude product is triturated from EtOAc/hexanes to afford the title compound as a beige solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06281227B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-486c2babe5274e5bb5ca505b439ce6a1 |
| Source note | uspto-grants-2001_08 |