HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluidine → 6-Methylquinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 3-Phenylprop-2-enoyl chloride | HCID 66023 | — |
| Product | 6-Methylquinolin-2(1H)-one | HCID 12237458 | — |
Reaction Steps
The title compound is prepared from p-toluidine and cinnamoyl chloride according to the procedure described in Synthesis 1975, 739. The crude product obtained is triturated in Et2O/hexanes and filtered to give the title compound as a beige solid which is used in the subsequent step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06281227B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-3d71f0813b1a4688b9e27379b9780961 |
| Source note | uspto-grants-2001_08 |