HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzyl bromide → HCID 54053133, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Reactant | (S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate | HCID 10750535 | — |
| Product | HCID 54053133 | HCID 54053133 | — |
Reaction Steps
The title compound is prepared from (2-oxopyrrolidin-3-(S)-yl)-carbamic acid tert-butyl ester as described in EXAMPLE 1, Part H using 4-nitrobenzyl bromide in place of 7-bromomethyl-1-chloro-isoquinoline. The crude product is purified by column chromatography eluting with a gradient of 10% EtOAc/CH2Cl2 to 25% EtOAc/CH2Cl2 to afford the title compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06281227B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-8c861eab508442d584808e770ee1257e |
| Source note | uspto-grants-2001_08 |