HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chlorobenzo[b]thiophene-2-sulfonyl chloride → 6-Chloro-benzo[b]thiophene-2-sulfonic acid (2-oxo-1-prop-2-ynyl-pyrrolidin-3-(s)-yl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chlorobenzo[b]thiophene-2-sulfonyl chloride | HCID 15158641 | — |
| Reactant | 3-(S)-amino-1-prop-2-ynyl-pyrrolidin-2-one hydrochloride | HCID 20680730 | — |
| Product | 6-Chloro-benzo[b]thiophene-2-sulfonic acid (2-oxo-1-prop-2-ynyl-pyrrolidin-3-(s)-yl)amide | HCID 53892522 | — |
Reaction Steps
The title compound is prepared as described in EXAMPLE 1, Part K using 6-chloro-benzo[b]thiophene-2-sulfonyl chloride and 3-(S)-amino-1-prop-2-ynyl-pyrrolidin-2-one hydrochloride as starting material. The crude product is isolated as a beige foam and used in the subsequent step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06281227B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-05187c3376004192a615c0c17db4dc1e |
| Source note | uspto-grants-2001_08 |