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HRID651676

反应详情

EQUATION

反应方程式

HRID 651676 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)n1c(CN2CC[C@H](N)C2=O)cc2cnccc21
HCID54368269

未命名化合物

结构：O=S(=O)(Cl)C=Cc1ccc(Cl)s1
HCID54463064

2-(5-Chlorothiophen-2-yl)ethene-1-sulfonyl chloride

C6H4Cl2O2S2

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)n1c(CN2CC[C@H](NS(=O)(=O)C=Cc3ccc(Cl)s3)C2=O)cc2cnccc21
HCID54483439

未命名化合物

PROCEDURE

实验过程

The title compound is prepared as described in EXAMPLE 56, Part A using 2-(5-chlorothiophen-2-yl)-ethenesulfonyl chloride and 2-[3-(S)-amino-2-oxo-pyrrolidin-1-ylmethyl)-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester as starting material. The crude product can be purified by column chromatography eluting with 5% MeOH/CH2Cl2 to give the title compound as a white solid or used in the subsequent step after an aqueous work-up without further purification.

WORKUP

后处理

  1. customThe title compound is prepared
  2. customThe crude product can be purified by column chromatography
  3. washeluting with 5% MeOH/CH2Cl2