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Malononitrile → Dihydro-2H-pyran-4,4(3H)-dicarbonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Malononitrile | HCID 8010 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 1,1'-Oxybis(2,2-dichloroethane) | HCID 62383 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | Dihydro-2H-pyran-4,4(3H)-dicarbonitrile | HCID 14537194 | 51.7% |
反応手順
A mixture of 28.6 g of dichloroethyl ether, 13.2 g of malononitrile, 55.28 g of potassium carbonate and 800 ml of acetonitrile was refluxed on a steam bath for 24 hours, then filtered while hot. The filtrate was evaporated and the residue crystallized with charcoal treatment from 100 ml of ethanol, giving 9.5 g of tetrahydro-4H-pyran-4,4-dicarbonitrile as colorless plates, mp 110-112° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06281365B1 |
| 出典データセット | uspto-grants-2001_08 |
| ORD ID | ord-2e4a3b4ca2244565a6f7509696dea21d |
| 出典メモ | uspto-grants-2001_08 |