1-Methyl-2-(tributylstannyl)-1H-imidazole → HCID 10203314, compound

HRID 651750Notes

Reaction equation

HRID 651750 reaction equation
Br[C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:12]3[C:13](=[O:28])[NH:14][C:15](=[O:27])[C:16]=3[C:17]3[C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]([CH3:26])[CH:18]=3)=[CH:7][N:8]2[CH3:11])=[CH:4][CH:3]=1.[CH3:29][N:30]1[CH:34]=[CH:33][N:32]=[C:31]1[Sn](CCCC)(CCCC)CCCC>>[CH3:26][N:19]1[C:20]2[C:25](=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:17]([C:16]2[C:15](=[O:27])[NH:14][C:13](=[O:28])[C:12]=2[C:6]2[C:5]3[C:9](=[CH:10][C:2]([C:31]4[N:30]([CH3:29])[CH:34]=[CH:33][N:32]=4)=[CH:3][CH:4]=3)[N:8]([CH3:11])[CH:7]=2)=[CH:18]1

Participants

3

Reactant 2

HCID 27632521-Methyl-2-(tributylstannyl)-1H-imidazoleHCID 21709059HCID 21709059, compound

Product 1

HCID 10203314HCID 10203314, compoundYield 38%

Procedure

3-(1-Methyl-1H-indol-3-yl)-4-[1-methyl-6-(1-methyl-1H-imidazol-2-yl)-1H-indol-3-yl]-pyrrole-2,5-dione (46 mg, 38%) was prepared from 3-(6-bromo-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)pyrrole-2,5-dione (120 mg, 0.28 mmol) and 1-methyl-2-(tributylstannyl)imidazole (0.8 mL, containing 50% 1-methyl-imidazole) (Molloy, K. C.; Waterfield, P. C.; Mahon, M. F. J. Organonetallic. Chem. 1989, 365, 61.)

Sources & evidence

ORD record
ord-766c92948796407289e57a512ebc4c8d
Source dataset
uspto-grants-2001_08
Patent number
US06281356B1

Reaction notes

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