2-(Tri-n-butylstannyl)thiophene → HCID 10277612, compound

HRID 651751Notes

Reaction equation

HRID 651751 reaction equation
I[C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:12]3[C:13](=[O:31])[NH:14][C:15](=[O:30])[C:16]=3[C:17]3[C:25]4[C:20](=[CH:21][C:22]([N+:26]([O-:28])=[O:27])=[CH:23][CH:24]=4)[N:19]([CH3:29])[CH:18]=3)=[CH:7][N:8]2[CH3:11])=[CH:4][CH:3]=1.C([Sn](CCCC)(CCCC)[C:37]1[S:38][CH:39]=[CH:40][CH:41]=1)CCC>>[CH3:29][N:19]1[C:20]2[C:25](=[CH:24][CH:23]=[C:22]([N+:26]([O-:28])=[O:27])[CH:21]=2)[C:17]([C:16]2[C:15](=[O:30])[NH:14][C:13](=[O:31])[C:12]=2[C:6]2[C:5]3[C:9](=[CH:10][C:2]([C:37]4[S:38][CH:39]=[CH:40][CH:41]=4)=[CH:3][CH:4]=3)[N:8]([CH3:11])[CH:7]=2)=[CH:18]1

Participants

3

Reactant 2

HCID 27793732-(Tri-n-butylstannyl)thiopheneHCID 15513672HCID 15513672, compound

Product 1

HCID 10277612HCID 10277612, compoundYield 37.3%

Procedure

3-(1-Methyl-6-nitro-1H-indol-3-yl)-4-(1-methyl-6-thiophen-2-yl-1H-indol-3yl)-pyrrole-2,5-dione (180 mg, 37%) was prepared from 3-(6-iodo-1-methyl-1H-indol-3-yl)-4-(1-methyl-6-nitro-1H-indol-3-yl)pyrrole-2,5-dione (525 mg, 1 mmol) and 2-(tributylstannyl)thiophene (0.98 mL, 3.09 mmol).

Sources & evidence

ORD record
ord-d9acf708a7234e789fbab67b6e8d2eb8
Source dataset
uspto-grants-2001_08
Patent number
US06281356B1

Reaction notes

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