Chloromethyl Methyl Ether → HCID 21709073, compound

HRID 651762Notes

Reaction equation

HRID 651762 reaction equation
[N:1]1([C:6]2[CH:14]=[C:13]3[C:9]([CH:10]=[CH:11][NH:12]3)=[CH:8][CH:7]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.Cl[CH2:16][O:17][CH3:18]>>[CH3:16][O:17][CH2:18][N:12]1[C:13]2[C:9](=[CH:8][CH:7]=[C:6]([N:1]3[CH2:5][CH2:4][CH2:3][CH2:2]3)[CH:14]=2)[CH:10]=[CH:11]1

Participants

3

Reactant 2

HCID 7864Chloromethyl Methyl EtherHCID 21709049HCID 21709049, compound

Product 1

HCID 21709073HCID 21709073, compound

Procedure

1-Methoxymethyl-6-pyrrolidin-1-yl-1H-indole was prepared from 6-pyrrolidin-1-yl-1H-indole ( example 12 e) in the same manner as example 1(a) using chloromethyl methylether as the alkylating agent.

Sources & evidence

ORD record
ord-dda18ef9ffd54206a5f6a3d5837f7580
Source dataset
uspto-grants-2001_08
Patent number
US06281356B1

Reaction notes

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