HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-methyl-6-pyrrolidin-1-yl-1H-indol-3-yl)-acetamide → 3-(6-Chloro-1-methyl-1H-indol-3-yl)-4-(1-methyl-6-pyrrolidin-1-yl-1H-indol-3-yl)pyrrole-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-methyl-6-pyrrolidin-1-yl-1H-indol-3-yl)-acetamide | HCID 21709040 | — |
| Reactant | methyl (6-chloro-1-methyl-1H-indol-3-yl)glyoxylate | HCID 21709087 | — |
| Product | 3-(6-Chloro-1-methyl-1H-indol-3-yl)-4-(1-methyl-6-pyrrolidin-1-yl-1H-indol-3-yl)pyrrole-2,5-dione | HCID 10204767 | 39.1% |
Reaction Steps
3-(6-Chloro-1-methyl-1H-indol-3-yl)-4-(1-methyl-6-pyrrolidin-1-yl-1H-indol-3-yl)pyrrole-2,5-dione (70 mg, 37%) was prepared from methyl (6-chloro-1-methyl-1H-indol-3-yl)glyoxylate (98 mg, 0.39 mmol) and (1-methyl-6-pyrrolidin-1-yl-1H-indol-3-yl)-acetamide (100 mg, 0.39 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06281356B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-d1de5ec6120949eab6a3cb7564597bca |
| Source note | uspto-grants-2001_08 |