HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → Ethyl 2-(Benzyloxycarbonylamino)-2-(acetoxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Ethyl 2-(benzyloxycarbonylamino)-2-(hydroxy)acetate | HCID 20233481 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ethyl 2-(Benzyloxycarbonylamino)-2-(acetoxy)acetate | HCID 15173153 | — |
Reaction Steps
The above ethyl 2-(benzyloxycarbonylamino)-2-(hydroxy)acetate (24.9 g), 34.2 ml of pyridine and 24.3 ml of acetic anhydride in 250 ml of tetrahydrofuran was stirred at room temperature for 30 minutes. It was then concentrated in vacuo, and dried under high vacuum for 4 hours to give 25.0 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04613462 |
| Source dataset | uspto-grants-1986_09 |
| ORD ID | ord-39d299af84f94a549fe5a4fc5d04ac3e |
| Source note | uspto-grants-1986_09 |