HCID 86757338, compound → HCID 86757337, compound

Participants

Reaction Steps

A solution of 0.061 g of 2(R)-[1(S)-(benzyloxycarbamoyl)-4-phenylbutyl]-N-[3-[2-(dimethylamino)ethyl]-2,5-dioxo-1-imidazolidinyl]-4-methylvaleramide in 10 ml of methanol was hydrogenated in the presence of 0.005 g of 10% palladium-on-carbon for 3 hours. The catalyst was removed by filtration and evaporation gave 0.048 g of 2(R)-[1(S)-(Hydroxycarbamoyl)-4-phenylbutyl]-N-[3-[2-(dimethylamino)ethyl]-2,5-dioxo-1-imidazolidinyl]-4-methylvaleramide in the form of a white solid.

Provenance & Evidence