HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinic anhydride → HCID 86587256, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinic anhydride | HCID 7922 | — |
| Reactant | Zidovudine | HCID 35370 | — |
| Product | HCID 86587256 | HCID 86587256 | — |
Reaction Steps
AZT was reacted with succinic anhydride to form AZT-succinic acid. This was reacted by the DCC/HOSu method with a mixture of Gly-Tris-Mono, Di and Tripalmitate (GTPn) which was prepared by catalytic hydrogenation of Z-GTPn. Column chromatography on silica gel and preparative HPLC were used to isolate the final compounds:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06281376B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-78b1ffd6bcca43c7ad4de6c71969617f |
| Source note | uspto-grants-2001_08 |