Benzaldehyde, 4-(phenylmethoxy)- → HCID 10490973, compound

HRID 651892Notes

Reaction equation

HRID 651892 reaction equation
[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][C:12]([CH:13]=O)=[CH:11][CH:10]=1)C1C=CC=CC=1.Cl.[C:18]([O:22][C:23](=[O:26])[CH2:24][NH2:25])([CH3:21])([CH3:20])[CH3:19].Cl.COC(=O)CN>>[C:18]([O:22][C:23](=[O:26])[CH2:24][NH:25][CH2:13][C:12]1[CH:11]=[CH:10][C:9]([O:8][CH3:1])=[CH:16][CH:15]=1)([CH3:21])([CH3:20])[CH3:19]

Participants

4

Reactant 3

HCID 78109Benzaldehyde, 4-(phenylmethoxy)-HCID 122755Glycine methyl ester hydrochlorideHCID 2725036Glycine tert-butyl ester hydrochloride

Product 1

HCID 10490973HCID 10490973, compound

Procedure

According to Example 1, Step 1, by substituting 4-methoxybenzaldehyde for 4-benzyloxybenzaldehyde and glycine tert-butyl ester hydrochloride for glycine methyl ester hydrochloride, the title compound was obtained as a yellow oil (80% yield).

Sources & evidence

ORD record
ord-e2f14ae9d2964ba085c0eaf37866ac9e
Source dataset
uspto-grants-2001_08
Patent number
US06281194B1

Reaction notes

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