Sulfuric Acid → 1-(2-Hydroxypropan-2-yl)-4-methylcyclohex-3-en-1-ol

Participants

Reaction Steps

A mixture of 26.0 g of 2,2,6-trimethyl-1-oxaspiro(2.5)oct-5-ene and 250 ml of 1% sulfuric acid was stirred magnetically for 20 hours, then extracted with four 100 ml portions of methylene chloride. The combined methylene chloride extracts was washed, dried, concentrated and Claisen-distilled to give 22.4 g of the desired product, b.p. 78°-81° C. (0.15 mm).

Provenance & Evidence