Hydrochloric Acid → HCID 13585476, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 4-phenylbutylphosphonous acid benzyl ester (1.0 gm, 0.0035 moles) in 10 ml acetone and 5 ml water was added a solution of potassium permanganate (0.16 gm, 0.0021 moles) in 5 ml water at 20° C. After the addition (2 minutes), the reaction mixture was stirred at 20° C. for 5 minutes and acidified to pH 1 using concentrated HCl acid. Saturated sodium bisulphite solution was added to the reaction mixture to get a cloudy white solution, which on extraction with ethyl acetate followed by solvent evaporation produced the title compound as a pale yellow oil in 87% (0.92 gm) yield.

Provenance & Evidence