N,N-Dimethyl-1,3-propanediamine → HCID 13747171, compound

HRID 651966Notes

Reaction equation

HRID 651966 reaction equation
Cl[C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]2[CH:9]=[N:10][NH:11][C:3]=12.[CH3:12][N:13]([CH3:18])[CH2:14][CH2:15][CH2:16][NH2:17]>>[CH3:12][N:13]([CH3:18])[CH2:14][CH2:15][CH2:16][NH:17][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]2[CH:9]=[N:10][NH:11][C:3]=12

Participants

3

Reactant 2

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 116798717-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine

Product 1

HCID 13747171HCID 13747171, compound

Procedure

The title compound was prepared from 7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine (D4) and 3-dimethylaminopropylamine by the method given in Example 2. On neutralization of the thus formed hydrochloride salt a clear solution was produced. After freeze drying, purification was carried out on Dowex 50W as described in Example 4, followed by crystallization from ethyl acetate to give the title compound as a white crystalline solid, m.p. 112°-117°.

Sources & evidence

ORD record
ord-6f5fca71c0d843368f0be60b6181a29b
Source dataset
uspto-grants-1987_06
Patent number
US04670432

Reaction notes

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