HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-(2-Chlorophenyl)pyrimidin-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Urea | HCID 1176 | — |
| Reactant | 2-(2-Chlorophenyl)-3-dimethylaminoprop-2-enal | HCID 54209358 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(2-Chlorophenyl)pyrimidin-2-ol | HCID 13605536 | — |
Reaction Steps
10 g of 2-(2-chlorophenyl)-3-dimethylaminoprop-2-enal (Example 1a) and 6 g of urea are heated under reflux in 40 ml of ethanol, in the presence of 10 ml of hydrochloric acid, for 4 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04613603 |
| Source dataset | uspto-grants-1986_09 |
| ORD ID | ord-76f80251635a4bb680ba89839b1ce4cf |
| Source note | uspto-grants-1986_09 |