1-[(4-Chlorophenyl)methyl]-4-(3-chloropropyl)piperazine → HCID 13607653, compound

HRID 651993Notes

Reaction equation

HRID 651993 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][N:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH2:17][O:18][C:19]3[CH:41]=[CH:40][C:22]4[C:23]([C:35]([O:37][CH2:38][CH3:39])=[O:36])=[C:24]([CH2:28]C5C=CC=CC=5)[C:25](=[O:27])[O:26][C:21]=4[CH:20]=3)[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.OC1C=CC2C(C(OCC)=O)=C(CC3C=CC=CC=3)C(=O)OC=2C=1.ClC1C=CC(CN2CCN(CCCCl)CC2)=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][N:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH2:17][O:18][C:19]3[CH:41]=[CH:40][C:22]4[C:23]([C:35]([O:37][CH2:38][CH3:39])=[O:36])=[C:24]([CH3:28])[C:25](=[O:27])[O:26][C:21]=4[CH:20]=3)[CH2:11][CH2:10]2)=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 133997271-[(4-Chlorophenyl)methyl]-4-(3-chloropropyl)piperazineHCID 20198975HCID 20198975, compoundHCID 20198982HCID 20198982, compound

Product 1

HCID 13607653HCID 13607653, compound

Procedure

ethyl 7-{3-{4-[(4-chlorophenyl)-methyl]-1-piperazinyl}-propoxy}-3-phenylmethyl-2H-1-benzopyran-2-one-4-carboxylate from ethyl 7-hydroxy-3-phenylmethyl-2H-1-benzopyran-2-one-4-carboxylate and 3-{4-[(4-chlorophenyl)-methyl]-1-piperazinyl}-propyl chloride.

Sources & evidence

ORD record
ord-fb53698801fe4c9fbc6eadfd91dfa54a
Source dataset
uspto-grants-1987_06
Patent number
US04670439

Reaction notes

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