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Methyl p-toluenesulfonate → HCID 178427651、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl p-toluenesulfonate | HCID 6645 | — |
| 反応物 | 11-(trifluoromethyl)-7H-benzimidazo[2,1-a]benz[de]isoquinoline-7-one | HCID 13206183 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | HCID 178427651 | HCID 178427651 | 50.5% |
反応手順
Six grams (0.018 m.) of 11-(trifluoromethyl)-7H-benzimidazo[2,1-a]benz[de]isoquinoline-7-one were heated to about 100° C. in 25 ml. of methyl p-toluenesulfonate for about 16 hours under a nitrogen atmosphere. After cooling, the solution was poured into ether. The solids were collected and recrystallized twice from methanol/ether to give 4.7 g. (50.5 percent yield) of the desired product, m.p. about 263°-265° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04670442 |
| 出典データセット | uspto-grants-1987_06 |
| ORD ID | ord-49074f5766bf48ae80829ae47e6c89e1 |
| 出典メモ | uspto-grants-1987_06 |