HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 65213Generated: October 30, 2026
Hydrogen Bromide → alpha-Oxo-4-(2-phenylethoxy)-benzeneacetaldehyde
https://huagongshe.com/reaction/65213
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 1-[4-(2-Phenylethoxy)phenyl]ethanone | HCID 13340057 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | alpha-Oxo-4-(2-phenylethoxy)-benzeneacetaldehyde | HCID 20234168 | — |
Reaction Steps
A 27.7 g portion of 4'-phenethyloxy-acetophenone was dissolved in 200 ml of dimethylsulfoxide. A 39.2 ml portion of 48% hydrobromic acid was added in small portions (exothermic), then the mixture was heated at 58° C. for 17 hours. The mixture was poured into 500 ml of ice and water and the solid was collected, washed with water and dried, giving the desired product as a yellow solid, mp 44°-59° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04613611 |
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| Source dataset | uspto-grants-1986_09 |
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| ORD ID | ord-21a127a8b165453f84140b8cd0a4e0c4 |
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| Source note | uspto-grants-1986_09 |
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