HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 4-Quinolinemethanol, 2-phenyl-alpha-(2-(4-piperidinyl)ethyl)-, (+-)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 1-(2-Phenyl-4-quinolyl)-3-(4-piperidyl)-1-propanone | HCID 20234118 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Quinolinemethanol, 2-phenyl-alpha-(2-(4-piperidinyl)ethyl)-, (+-)- | HCID 3068228 | — |
Reaction Steps
The operation was as in Example 1, except that 14 g of 1-(2-phenyl-4-quinolyl)-3-(4-piperidyl)-1-propanone and 2.3 g of sodium borohydride in 300 ml of methanol were used. After recrystallization of the crude product in isopropanol, 7 g of 1-(2-phenyl-4-quinolyl)-3-(4-piperidyl)-1-propanol (racemic) were obtained, which melted at 162° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04613607 |
| Source dataset | uspto-grants-1986_09 |
| ORD ID | ord-225a0a7545e24717a4ea3d58050b1e41 |
| Source note | uspto-grants-1986_09 |