HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenylhydrazine hydrochloride → HCID 86741573, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenylhydrazine hydrochloride | HCID 69981 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 4-(2-Fluorobenzoyl)-1-methylpiperidine | HCID 13180317 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 86741573 | HCID 86741573 | 23.1% |
Reaction Steps
A stirred mixture of 21.8 g of 4-(2-fluorobenzoyl)-1-methylpiperidine, 20.25 g of 4-fluorophenyl hydrazine hydrochloride and 25.0 g of sodium acetate in 420 ml of n-butanol was heated under reflux for 8 hrs. The mixture was cooled, filtered, and concentrated. The residue was washed with ether to give 7.5 g (23%) of 4-(2-fluorobenzoyl)-1-methylpiperidine 4-fluorophenylhydrazone, mp 125°-126° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04670447 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-d877a9b76af54628836ce0c9d0d84a25 |
| Source note | uspto-grants-1987_06 |