4-Hydroxy-2,2,6,6-tetramethylpiperidine → HCID 54408028, compound

HRID 652208Notes

Reaction equation

HRID 652208 reaction equation
[CH2:1]([O:3][C:4]([CH2:6][N:7]([CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[C:8]([CH2:10][CH2:11][CH2:12][CH3:13])=[O:9])=[O:5])[CH3:2].C[C:21]1([CH3:30])[CH2:26]C(O)[CH2:24][C:23]([CH3:29])([CH3:28])[NH:22]1.[CH3:31][C:32]([CH3:35])([O-])[CH3:33].[K+]>C1(C)C=CC=CC=1>[CH3:31][C:32]1([CH3:35])[CH2:33][CH:1]([O:3][C:4]([CH2:6][N:7]([CH2:14][C:15]([O:17][CH:18]2[CH2:29][C:23]([CH3:24])([CH3:28])[NH:22][C:21]([CH3:26])([CH3:30])[CH2:19]2)=[O:16])[C:8]([CH2:10][CH2:11][CH2:12][CH3:13])=[O:9])=[O:5])[CH2:2][C:21]([CH3:30])([CH3:26])[NH:22]1

Participants

5

Reactant 3

HCID 754714-Hydroxy-2,2,6,6-tetramethylpiperidineHCID 23665647Potassium tert-butoxideHCID 54415895HCID 54415895, compound

Product 1

HCID 54408028HCID 54408028, compoundYield 152.8%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To the same reactor as in Example 1 were added 23.3 g (0.09 mole) of N,N-bis(ethoxycarbonylmethyl)butanecarboxylic acid amide, 28.2 g (0.18 mole) of 2,2,6,6-tetramethyl-4-piperidinol, 50 ml of toluene and 0.5 g (0.04 mole) of potassium tert-butoxide. Reaction and after-treatment were carried out in the same manner as in Example 1 to obtain 30.3 g of N,N-bis(2,2,6,6-tetramethyl-4-piperidinyloxycarbonylmethyl)butanecarboxylic acid amide as a white crystal (yield, 70%). Melting point, 96°-98° C.

Workup

  1. customReaction
  2. customto obtain

Sources & evidence

ORD record
ord-dd33a800116845e599b1415987f81a2a
Source dataset
uspto-grants-1987_06
Patent number
US04670489

Reaction notes

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