HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl iodide → HCID 13911279, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl iodide | HCID 10962 | — |
| Reactant | 3-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]thieno[3,2-d]pyrimidine-2,4-dione | HCID 13911278 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 13911279 | HCID 13911279 | 56% |
Reaction Steps
The title compound was produced following the procedure of Example 13 using dimethylformamide as the solvent, the thienopyrimidine-2,4-dione (2.0 g, 5.17 mmol) from Example 19, and butyl iodide as the alkylating agent. The title compound was isolated in 56% yield (1.28 g) after recrystallization from EtOH, mp 139°-140° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04670560 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-27c65857ab184ff68b0a013677a88802 |
| Source note | uspto-grants-1987_06 |