HCID 13911209, compound → HCID 13911210, compound

Participants

Reaction Steps

A solution of 48.0 g (0.166 mole) of 7-chloro-3-methylthio-4-phenylindolin-2-one was treated with 380 g of a washed commercial preparation of Raney-nickel under vigorous agitation for 5 min. The mixture was filtered and the filtrate was concentrated under reduced pressure to give a pale yellow powder as residue. The residue was triturated with hot absolute ethanol to give 38.1 g (94%) of the title compound as white powder, m.p. 234°-236° C.

Provenance & Evidence