Thionyl Chloride → Fluorocinnamoyl chloride

HRID 652281Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 652281
[F:1][C:2](=[CH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:3](O)=[O:4].S(Cl)([Cl:15])=O>>[F:1][C:2](=[CH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:3]([Cl:15])=[O:4]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 98321Fluorocinnamic acid

Produkt 1

HCID 54157638Fluorocinnamoyl chloride

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

To α-fluorocinnamic acid (5.48 g, 33 mM), thionyl chloride (40 ml) was added, and the thus obtained mixture was stirred at 80° C. under refluxing for 2 hours. After cooling it to a room temperature, the unreacted thionyl chloride was distilled off under reduced pressure to give a syrup-like α-fluorocinnamoyl chloride.

Aufarbeitung

  1. temperatureunder refluxing for 2 hours
  2. temperatureAfter cooling it to a room temperature
  3. distillationthe unreacted thionyl chloride was distilled off under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-1abb513cbbea41038d3b74bfe741a245
Quelldatensatz
uspto-grants-1987_06
Patentnummer
US04670584

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