Sulfuric Acid → 4-Acetoxy-4'-acetylbiphenyl

HRID 652282Notes

Reaction equation

HRID 652282 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:16])[CH3:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.S(=O)(=O)(O)O.[C:22](OC(=O)C)(=[O:24])[CH3:23]>>[C:22]([O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:16])[CH3:15])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1)(=[O:24])[CH3:23]

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 7918Acetic AnhydrideHCID 103308064-(4-Acetylphenyl)phenol

Product 1

HCID 135310454-Acetoxy-4'-acetylbiphenylYield 97%

Procedure

10.5 g of 4-hydroxy-4'-acetylbiphenyl (C) obtained in Example 1 was heated together with 20 ml of acetic anhydride in the presence of a small amount of concentrated sulfuric acid. Crude crystals thus obtained were recrystallized from carbon tetrachloride to obtain 12.5 g of 4-acetoxy-4'-acetylbiphenyl (1): ##STR51##

Workup

  1. customCrude crystals thus obtained
  2. customwere recrystallized from carbon tetrachloride

Sources & evidence

ORD record
ord-f180c374cfd249518db9472414c7b524
Source dataset
uspto-grants-1987_06
Patent number
US04670581

Reaction notes

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