Acetic Anhydride → 4-Acetoxy-4'-isopropenylbiphenyl

HRID 652288Notes

Reaction equation

HRID 652288 reaction equation
[C:1](OC(=O)C)(=O)C.[C:8]([O:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[CH:23]=[CH:22][C:21]([C:24](=O)[CH3:25])=[CH:20][CH:19]=2)=[CH:14][CH:13]=1)(=[O:10])[CH3:9]>O>[C:8]([O:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[CH:23]=[CH:22][C:21]([C:24]([CH3:25])=[CH2:1])=[CH:20][CH:19]=2)=[CH:14][CH:13]=1)(=[O:10])[CH3:9]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 135310454-Acetoxy-4'-acetylbiphenyl

Product 1

HCID 135310484-Acetoxy-4'-isopropenylbiphenylYield 60%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
80 °C

Procedure

10 ml of acetic anhydride was charged in a flask provided with a reflux condenser and a stirrer. Then, 1 g of 4-hydroxy-4'-isopropenylbiphenyl obtained in Example 2 was added thereto and the mixture was stirred at 80° C. for 1 hr to effect the reaction. The reaction solution was poured into water and the resulting crystals were separated and recrystallized from methanol to obtain 0.72 g of 4-acetoxy-4'-isopropenylbiphenyl (53) in the form of white crystals. ##STR158##

Workup

  1. customprovided with a reflux condenser and a stirrer
  2. customthe reaction
  3. customthe resulting crystals were separated
  4. customrecrystallized from methanol

Sources & evidence

ORD record
ord-f1b4afee7f9b429b98e804c85ce1d58c
Source dataset
uspto-grants-1987_06
Patent number
US04670581

Reaction notes

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