Water → HCID 13280856, compound

HRID 652332Notes

Reaction equation

HRID 652332 reaction equation
B(Br)(Br)Br.C[O:6][C:7]1[CH:8]=[C:9]([NH:13][C:14](=[O:19])[C:15]([O:17][CH3:18])=[O:16])[CH:10]=[CH:11][CH:12]=1.O>C(Cl)Cl>[OH:6][C:7]1[CH:8]=[C:9]([NH:13][C:14](=[O:19])[C:15]([O:17][CH3:18])=[O:16])[CH:10]=[CH:11][CH:12]=1

Participants

5

Reactant 3

HCID 962WaterHCID 25134Boron tribromideHCID 19818641HCID 19818641, compound

Product 1

HCID 13280856HCID 13280856, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

5 g of boron tribromide are added dropwise to a solution, cooled to -78° C., of 2 g of methyl N-(3-methoxyphenyl)-oxamate in 20 ml of methylene chloride in the course of 5 minutes. The mixture is stirred at room temperature for 5 hours, 5 ml of water are added, with cooling, and the organic phase is separated off. Drying over sodium sulfate and evaporation gives methyl N-(3-hydroxyphenyl)-oxamate.

Workup

  1. temperaturewith cooling
  2. customthe organic phase is separated off
  3. dry with materialDrying over sodium sulfate and evaporation

Sources & evidence

ORD record
ord-69a554ae66ce43d4bb610103ea2f69e4
Source dataset
uspto-grants-1987_06
Patent number
US04670604

Reaction notes

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