1-Methylimidazole → HCID 178490138, compound

HRID 65239Notes

Reaction equation

HRID 65239 reaction equation
[CH3:1][N:2]1[CH:6]=[CH:5][N:4]=[CH:3]1.[Br:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1>>[Br-:7].[CH3:18][O:17][C:14]1[CH:15]=[CH:16][C:11]([CH2:10][CH2:9][CH2:8][N+:4]2[CH:5]=[CH:6][N:2]([CH3:1])[CH:3]=2)=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 13901-MethylimidazoleHCID 127769961-(3-Bromopropyl)-4-methoxybenzene

Product 1

HCID 178490138HCID 178490138, compound

Conditions

Temperature
140 °C

Procedure

A mixture of 2.50 g (0.03 mole) of 1-methyl-1H-imidazole and 6.9 g (0.03 mole) of 1-(3-bromopropyl)-4-methoxybenzene is heated at 140° C. for 1.5 hours. Follow the progress of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5). At the completion, the cooled reaction product is triturated thoroughly with ether and on drying, provides the title compound.

Workup

  1. customthe progress of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5)
  2. customAt the completion, the cooled reaction product
  3. customis triturated thoroughly with ether
  4. customon drying

Sources & evidence

ORD record
ord-b4506c6b1dc343459d9a01c6adf7bcea
Source dataset
uspto-grants-1986_09
Patent number
US04613609

Reaction notes

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