Nitric Acid → HCID 21298687, compound

HRID 652402Notes

Reaction equation

HRID 652402 reaction equation
[N+:1]([O-:4])(O)=[O:2].[CH2:5]([O:12][C:13]1[CH:14]=[CH:15][C:16]2[O:21][CH2:20][C:19](=[O:22])[NH:18][C:17]=2[CH:23]=1)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>C(O)(=O)C>[N+:1]([C:14]1[C:13]([O:12][CH2:5][C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=2)=[CH:23][C:17]2[NH:18][C:19](=[O:22])[CH2:20][O:21][C:16]=2[CH:15]=1)([O-:4])=[O:2]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 22312863HCID 22312863, compound

Product 1

HCID 21298687HCID 21298687, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Aqueous 65% nitric acid (5.04 g, 0.052 mole) was added under stirring at room temperature to the oxazinone ((d), 12 g, 0.047 mole) in acetic acid (ml 30). After 1 hour, the separated solid was filtered and washed with acetic acid to give the nitroxazinone ((e), 9 g, 64%) as yellow prisms. The product structure was confirmed by NMR analysis.

Workup

  1. filtrationthe separated solid was filtered
  2. washwashed with acetic acid

Sources & evidence

ORD record
ord-9dfaad56e51647029d7cc82427c40cca
Source dataset
uspto-grants-1987_06
Patent number
US04672013

Reaction notes

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