1-Heptyl-1H-imidazole → HCID 178443954, compound

HRID 65241Notes

Reaction equation

HRID 65241 reaction equation
[CH2:1]([N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[Br:13][CH2:14][CH2:15][CH2:16][C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=1>>[Br-:13].[CH2:1]([N+:8]1[CH:12]=[CH:11][N:10]([CH2:14][CH2:15][CH2:16][C:17]2[CH:18]=[CH:19][C:20]([O:23][CH3:24])=[CH:21][CH:22]=2)[CH:9]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Participants

3

Reactant 2

HCID 1866691-Heptyl-1H-imidazoleHCID 127769961-(3-Bromopropyl)-4-methoxybenzene

Product 1

HCID 178443954HCID 178443954, compound

Conditions

Temperature
140 °C

Procedure

A mixture of 2.5 g (0.015 mole) of 1-heptyl-1H-imidazole and 3.45 g (0.015 mole) of 1-(3-bromopropyl)-4-methoxybenzene is heated at 140° C. for about 1.5 hours. Follow the progress of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5). At the completion of the reaction, the cooled reaction product is triturated thoroughly with ether and on drying, provides the title compound.

Workup

  1. customthe progress of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5)
  2. customAt the completion of the reaction
  3. customthe cooled reaction product
  4. customis triturated thoroughly with ether
  5. customon drying

Sources & evidence

ORD record
ord-4c6aa91630f043c2aac6518958935801
Source dataset
uspto-grants-1986_09
Patent number
US04613609

Reaction notes

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