Phosphoric Acid → HCID 20197207, compound

Participants

Reaction Steps

15.3 g 3-butylamino-2,3,4,5-tetrahydro-1-benzoxepin-5-ol hydrochloride were stirred for four hours at room temperature in 80 ml of an 85 percent aqueous phosphoric acid solution. Subsequently, the solution was poured over 100 g of ice, and the mixture was worked up as described in Example 1. 12.1 g of 3-butylamino-2,3-dihydro-1-benzoxepine hydrochloride were obtained. Melting point: 138 degrees C.

Provenance & Evidence