Phosphorus sulfide (P2S5) → HCID 13531961, compound

HRID 652415Notes

Reaction equation

HRID 652415 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([NH:7][C:8](=O)[CH2:9][O:10][C:11]2[C:16]([Cl:17])=[CH:15][C:14]([Cl:18])=[CH:13][C:12]=2[Cl:19])[CH:2]=1.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:22]>C1(C)C=CC=CC=1>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([NH:7][C:8](=[S:22])[CH2:9][O:10][C:11]2[C:16]([Cl:17])=[CH:15][C:14]([Cl:18])=[CH:13][C:12]=2[Cl:19])[CH:2]=1

Participants

4

Reactant 2

HCID 14817Phosphorus sulfide (P2S5)2×HCID 293787n-(pyridin-3-yl)-2-(2,4,6-trichlorophenoxy)acetamide

Product 1

HCID 13531961HCID 13531961, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

N-3-pyridyl-2,4,6-trichlorophenoxyacetamide, 33.4 gm, is added to 200 ml of toluene. 22.2 gm of phosphorus pentasulfide (P2S5) is then added to the system. The system is exposed to microwave radiation throughout in order to aid in the dispersion of the phosphorus pentasulfide. The reaction is stirred for 16 hours at ambient temperature. The reaction is then stopped and the solution filtered. The toluene is removed by stripping to give the title compound.

Workup

  1. filtrationthe solution filtered
  2. customThe toluene is removed

Sources & evidence

ORD record
ord-4e9fd157cda247e9b08fd2a678b34820
Source dataset
uspto-grants-1987_06
Patent number
US04672065

Reaction notes

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