Pyridine, 3-(4-aminobutyl)- → 8-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[4-(3-pyridinyl)butyl]octanamide

Participants

Role	Name	HCID	Charge
Reactant	Pyridine, 3-(4-aminobutyl)-	HCID 72927	—
Reactant	8-(4-Acetyl-3-hydroxy-2-propylphenoxy)octanoic acid	HCID 13753875	—
Product	8-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[4-(3-pyridinyl)butyl]octanamide	HCID 13912784	—

Reaction Steps

8-(4-Acetyl-3-hydroxy-2-propylphenoxy)octanoic acid was allowed to react with 3-pyridine butanamine according to procedure A and the product was purified by high performance liquid chromatography (HPLC) to give 8-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[4-(3-pyridinyl)butyl]octanamide, the title compound, mp 48°-51° (from ether-hexane) in 83% yield.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04672066
Source dataset	uspto-grants-1987_06
ORD ID	ord-88a70e5beb3f4bb8859935641c681836
Source note	uspto-grants-1987_06