HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Pyridin-3-yl)ethan-1-amine → 4-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[2(3-pyridinyl)ethyl]butanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Pyridin-3-yl)ethan-1-amine | HCID 854051 | — |
| Reactant | 4-(4-Acetyl-3-hydroxy-2-propylphenoxy)butanoic acid | HCID 13753871 | — |
| Product | 4-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[2(3-pyridinyl)ethyl]butanamide | HCID 13912783 | — |
Reaction Steps
4-(4-Acetyl-3-hydroxy-2-propylphenoxy)butanoic acid was allowed to react with 3-pyridine ethanamine according to procedure A and the product was purified by chromatography on silica gel to give 4-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[2(3-pyridinyl)ethyl]butanamide, the title compound, mp 94°-96° (from methylene chloride-ether) in 74% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04672066 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-711eb606e25b4410943fecd4c7eb892e |
| Source note | uspto-grants-1987_06 |