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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 652487Generated: October 31, 2026

4-Pyridineethanamine → 6-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[2-(4-pyridinyl)ethyl]hexanamide

https://huagongshe.com/reaction/652487

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PyridineethanamineHCID 83275—
Reactant6-(4-Acetyl-3-hydroxy-2-propylphenoxy)hexanoic acidHCID 13753873—
Product6-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[2-(4-pyridinyl)ethyl]hexanamideHCID 13912779—

Reaction Steps

6-(4-Acetyl-3-hydroxy-2-propylphenoxy)hexanoic acid was allowed to react with 4-pyridine ethanamine according to procedure A and the product was purified by chromatography on silica gel to give 6-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[2-(4-pyridinyl)ethyl]hexanamide, the title compound, mp 80°-83° (from methylene chloride-ether) in 58% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04672066
Source datasetuspto-grants-1987_06
ORD IDord-97388d9a61cd40c5ba59ea038fc22592
Source noteuspto-grants-1987_06